Event:

Forensics with Oxford Nanopore Technologies

Date: Tuesday 10th November 2020

Time: 3:00 pm (UK time)/ 10:00 am (EST)

Please join us for the next seminar in this series in which you will first hear from James Brayer, Associate Director - Market Development, Oxford Nanopore Technologies Ltd., who will give an overview of the platform before we are joined by Roxanne R. Zascavage, an Assistant Professor at the University of Texas at Arlington, who will present her latest research with nanopore sequencing.

There will also be an opportunity to submit questions throughout the talks which will be answered in the live Q&A session following the presentations.

Please register below to attend this webinar. You will receive a confirmation of your place from events@nanoporetech.com

Speaker information

Roxanne R. Zascavage, University of Texas at Arlington

Roxanne Zascavage is an Assistant Professor in the Department of Criminology and Criminal Justice at the University of Texas at  Arlington. She specializes in the application of Oxford Nanopore Sequencing Technology to forensic biology, focusing on developing novel and improved approaches to human identification.

Abstract

Forensic Short Tandem Repeat Analysis on the MinION Device

Forensic DNA analysis exploits the high variability of short tandem repeat (STR) markers to differentiate individuals. Typical STR typing workflow depends upon size-based separation and detection via capillary electrophoresis (CE) but the profiles generated mask sequence-level variations. Detection of hidden nucleotide variations within and around forensic STR markers greatly increases the resolving power and aids in interpretation of challenging samples. Here we discuss our ongoing development of a reliable
workflow for forensic STR interrogation on the MinION device, which will provide the most comprehensive representation of the genetic variability at STR loci, while assuring compatibility with current CE-generated profiles.

James Brayer, Associate Director - Market Development, Oxford Nanopore Technologies Ltd. 

James joined Oxford Nanopore Technologies in July 2012 and is an experienced life sciences and commercial professional. He has held research roles at the Forsyth Dental Institute and Massachusetts General Hospital, and commercial roles at Affymetrix, Helicos BioSciences and RainDance Technologies before joining Oxford Nanopore. Throughout his career he has worked in commercial roles as a field scientist, product manager and market development. During this time, James has built a passion for working with customers to help with their research and achieve success. At Oxford Nanopore, James is focused on developing relationships with Key Opinion Leaders and scientists to develop new applications utilizing the Oxford Nanopore platform.