Thank you for your interest in long-read nanopore pharmacogenomic sequencing (PGx workflow). This product is currently moving to the Beta testing phase and will available soon for testing for selected users.
Conventional microarray and short-read sequencing technologies have limited resolution for pharmacogenomic sequencing. Nanopore long-read sequencing technology overcomes these limitations by providing the ability to disambiguate pseudogene homology, detect and characterize complicated structural variants and gene-pseudogene conversions, and phase haplotypes. In collaboration with Twist Bioscience, Oxford Nanopore has demonstrated a sample-to-star allele workflow with high performance.
The end-to-end workflow combines the Twist Alliance Long-Read PGx Panel with Oxford Nanopore Technology library preparation, sequencing, data analysis, and star allele calling (Figure 1). The Twist panel captures 49 genes covering 2 Mb of the genome (Figure 2).
Register here to participate in the Beta testing programme for the PGx Sequencing workflow:
This form allows you to confirm your interest for the PGx workflow. If you are selected to participate, we will contact you with further information regarding this workflow. Please contact us at beta.programme@nanoporetech.com if you need any assistance.
Please note that the * signifies that a question is mandatory for submission.